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The New England Journal of Medicine

COVID Vaccine An mRNA Vaccine against SARS-CoV-2 — Preliminary Report The severe acute respiratory syn- drome coronavirus 2 (SARS-CoV-2) emerged in December 2019 and spread globally, causing a pandemic of respiratory illness desig- nated coronavirus disease 2019 (Covid-19).1 The urgent need for vaccines prompted an interna- tional response, with more than 120 candidate SARS-CoV-2 vaccines in development